Small spheno-ethmoidal meningoencephalocele versus ethmoidal mucocele in spontaneous intracranial hypotension

Small spheno-ethmoidal meningoencephalocele versus ethmoidal mucocele in spontaneous intracranial hypotension

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Background: Meningoencephalocele is defined as an abnormal sac of brain tissue and meninges extending beyond natural skull margins, often leading to cerebrospinal fluid (CSF) leakage.When this condition arises in the spheno-ethmoidal region, the diagnosis becomes more challenging as AC-AC Transformers it can be mistaken for other nasal pathologies, such as mucocele.Research question: We show in this case report a non-congenital sphenoethmoidal meningoencephalocele causing rhinoliquoral fistula and spontaneous intracranial hypotension.

Results: this 65-year-old woman presented with sporadic rhinoliquorrhoea associated with orthostatic headache, nausea and dizziness.Brain MRI revealed a small lesion of an ethmoidal sinus, which was successfully treated with endoscopic endonasal surgery.Histology confirmed the presence of meningoencephalic tissue positive for S100 protein on immunohistochemistry.

Conclusions: When dealing with lesions of the paranasal sinuses in contact with the anterior skull base, rhinoliquorrhoea presence suggests meningoencephalocele.In dubious cases, a proper workup, including a thorough clinical history and neurological Sex Toys for Men examination, specific imaging, and a direct search of CSF-like markers, is essential to support the differential diagnosis.In such cases, a transnasal endoscopic surgical approach is recommended to obtain a final histological diagnosis and to perform eventual dural plastic surgery.